miRNA description for let-7i-5p
miRNA accession let-7i-5p
Species Homo sapiens
 let-7i-5p identified in exosomes derived from the following tissue/cell type
Lung epithelial cells [Exosomes] 31762962   
Lung epithelial cells [Exosomes] 31762962   
Mesenchymal stem cells [Exosomes] 33479185   
Mesenchymal stem cells [Extracellular vesicles] 34596354   
Plasma [Exosomes] 29295981   
Plasma [Exosomes] 29295981   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Urine [Exosomes] 24352158   
 Experiment description of studies that identified let-7i-5p in exosomes
1
Experiment ID2320
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SampleLung epithelial cells
Sample nameBEAS-2B
Molecules identified in the studymiRNA
Methods used in the studyqRT-PCR
EV-TRACK -
2
Experiment ID2321
Identified moleculemiRNA
Identification method qRT-PCR
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SampleLung epithelial cells
Sample nameBEAS-2B
Molecules identified in the studymiRNA
Methods used in the studyqRT-PCR
EV-TRACK -
3
Experiment ID1526
Identified moleculemiRNA
Identification method Microarray
PubMed ID 33479185   
OrganismHomo sapiens
Experiment descriptionHuman umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke
AuthorsZhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X.
Journal name Aging
Publication year2021
SampleMesenchymal stem cells
Sample namehUMSCs
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Microarray
EV-TRACK -
4
Experiment ID3202
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 34596354   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p
AuthorsLee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG.
Journal name J Extracell Vesicles
Publication year2021
SampleMesenchymal stem cells
Sample nameAdipose tissue-derived stem cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyFlow cytometry
Small RNA sequencing
ddPCR
EV-TRACK -
5
Experiment ID2276
Identified moleculemiRNA
Identification method Microarray
PubMed ID 29295981   
OrganismHomo sapiens
Experiment descriptionCirculating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis
AuthorsKimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T.
Journal name Nat Commun
Publication year2018
SamplePlasma
Sample nameHealthy controls
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Microarray
RT-qPCR
EV-TRACK -
6
Experiment ID2277
Identified moleculemiRNA
Identification method Microarray
PubMed ID 29295981   
OrganismHomo sapiens
Experiment descriptionCirculating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis
AuthorsKimura K, Hohjoh H, Fukuoka M, Sato W, Oki S, Tomi C, Yamaguchi H, Kondo T, Takahashi R, Yamamura T.
Journal name Nat Commun
Publication year2018
SamplePlasma
Sample nameMultiple sclerosis
Molecules identified in the studymiRNA
Methods used in the studyMicroarray
RT-qPCR
EV-TRACK -
7
Experiment ID2318
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameSmokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -
8
Experiment ID2319
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameCOPD patients
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -
9
Experiment ID1031
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (ExoRNeasy)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
10
Experiment ID1032
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (ExoRNeasy)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
11
Experiment ID1033
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (qEV)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
12
Experiment ID1034
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (qEV)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
13
Experiment ID1035
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (Exo-spin)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
14
Experiment ID1036
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (Exo-spin)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
15
Experiment ID1037
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (miRCURY)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
16
Experiment ID1038
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (miRCURY)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
17
Experiment ID357
Identified moleculemiRNA
Identification method RNA deep sequencing
PubMed ID 24352158   
OrganismHomo sapiens
Experiment descriptionCharacterization and deep sequencing analysis of exosomal miRNA in human urine
AuthorsLesley Cheng, Xin Sun, Bradley M. Coleman, Andrew F. Hill
Journal name Kidney Int
Publication year2014
SampleUrine
Sample nameUrine - Normal
Molecules identified in the studymiRNA
Methods used in the studyRNA deep sequencing
EV-TRACK EV140147: EV-METRIC:44%, 0%, 22%